![]() ![]() To compare read mapping and gene expression profiles across libraries for neurotranscriptome differential expression, we mapped back RNA-seq reads to the C. Douglas Mesquita Silva Plus Maze AquariumĪ third plus maze aquarium was used for spatial and object recognition tests.Ĭompared with IE, the EE fish showed greater learning rates, body length, and body weight.Īfter behavioral tests, whole brain tissue was taken, stored in RNA-later, and then homogenized for DNA sequencing after conversion of isolated RNA. ![]() Douglas Mesquita Silva Plus Maze Aquariumįish were housed for 192 days in either EE or in an impoverished environment (IE) aquarium.ĮE contained toys, natural plants, and a 12-hday water stream for voluntary exercise, whereas IE had no toys, plants, or water stream. ![]() Surgical excision of the labial lesion was done, with no signs of recurrence after four months. After medical evaluation, no amyloid deposits were found in other tissues and the condition was classified as cutaneous amyloidosis. Congo red staining was positive, with apple-green birefringence under polarized light, resulting in the diagnosis of amyloidosis. Histopathologic analysis revealed deposition of a hyaline, acellular, eosinophilic, and amorphous material on the connective tissue. With the clinical hypothesis of mesenchymal or glandular neoplasm, an incisional biopsy was performed. A 57-year-old female patient presented with a well-delimited, asymptomatic, submucosal fibrous nodule, measuring 15 mm, localized on the left lower labial mucosa, covered by healthy mucosa, with 2 years of onset. Amyloidosis represents a group of rare diseases characterized by extracellular deposition of insoluble amyloid fibrils. ![]()
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